Elucidating the precise pharmacological mechanism of action (MOA) of naturally occurring compounds is often challenging. Whilst Tarselli et al. (60) developed the first de novo artificial pathway to conolidine and showcased that this naturally occurring compound correctly suppresses responses to both chemically induced and inflammation-derived pain, the pharmacologic target https://conneregdzv.pages10.com/conoldine-alternative-natural-pain-relief-an-overview-73010686