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DNA ligases seal 5′-PO4 and three′-OH polynucleotide ends by means of 3 nucleotidyl transfer measures involving ligase-adenylate and DNA-adenylate intermediates. DNA ligases are vital guardians of genomic integrity, and ligase dysfunction underlies human genetic disease syndromes. Crystal buildings of DNA ligases certain to nucleotide and nucleic acid substrates have https://sbobet17038.blogs100.com/28500283/not-known-details-about-online-betting-site

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